The lab manager will be part of the Lippmann Laboratory in the Department of Chemical and Biomolecular Engineering. The lab manager will be a key contributor to the laboratory and will be responsible for assisting in day to day operations and experiments. The position requires ordering necessary supplies and materials, ensuring that the equipment is well-maintained, and keeping the laboratory organized. The lab manager is also expected to perform key duties, potentially including but not limited to in vitro and in vivo experiments. Specifically, the lab manager will be independently tasked with developing and implementing in vivo disease models, and will train and manage all student activities that involve the use of such models. The lab manager will work with students and postdoctoral associates in the lab and will report directly to the Principal Investigator.
The Lippmann Laboratory at Vanderbilt University performs cutting-edge research in the areas of neurovascular/neurodegenerative disease, human induced pluripotent stem cell (iPSC) differentiation, fabrication of in vitro tissue models, CRISPR screening, and in vitro selection/directed evolution. We use cellular, engineering, biological, molecular, and quantitative approaches to understand the mechanisms of neurovascular dysfunction in neurodegeneration. We are especially interested in the molecular identity of the blood-brain barrier and its role in neurodegeneration.
The Department of Chemical and Biomolecular Engineering fosters an interdisciplinary environment for innovative research. The department is interested in a wide range of research areas--from energy to nanomaterials to cancer immunotherapy. The department is highly collaborative and works with departments and institutes across campus, including the Vanderbilt University Medical Center.
Duties and Responsibilities
Conduct and Evaluate Experiments
Understand and follow experimental protocols (may include PCR/molecular cloning, western blotting, immunohistochemistry)
Record, compile, interpret, and communicate data / results
Follow University safety protocols and serve as resource for all lab personnel
Conduct in vivo studies and experiments in rodents in a routine, efficient manner with minimal supervision
Oversight and maintenance of mouse colonies, including breeding, genotyping, and record keeping
Responsible for mouse handling, including injections, perfusions, and tissue harvesting
Responsible for establishing mouse models of neurodegenerative disease and training students on the use of such models
Maintain and Manage the laboratory facilities
Maintain all equipment according to manufacturer and University guidelines
Prepare laboratory for experiments and maintain sterile conditions as required
Maintain inventories of all supplies and reagents
Provide administrative support for the PI
Implement new programs, tests, methods, instrumentation, and procedures by investigating alternatives, preparing proposals, developing and performing parallel testing, and monitoring progress
Independently assure compliance with all regulatory requirements of the University, Sponsors and state/federal governments
Evaluate and oversee procedures for chemical storage and disposal of biohazard waste
Serve as primary purchasing officer for the lab
Communicate with vendors, sales representatives, and service contractors to purchase supplies, obtain specifications and quotes for new equipment
Train and Supervise new lab members and research collaborators
Supervise technical staff and students and oversee laboratory activities
Coordinate and review the work of others as it relates to lab activities
Ensure that all lab personnel have completed the requisite training and follow established SOPs
Profile of an Ideal Candidate
A Bachelor's degree in a relevant field from an accredited institution of higher education is necessary.
3-5 years of experience is preferred
Ability to maintain a high level of organization is necessary
Ability to handle animals is necessary
A desire to learn, especially outside of one's comfort zone, is necessary
A high level of motivation and initiative is necessary
Ability to maintain quality and safety standards is preferred
Ability to understand and follow basic research protocols and procedures is preferred
Ability to develop scientific research protocols and procedures is preferred
Ability to analyze and interpret scientific data is preferred
Ability to understand and follow complex, detailed technical instructions is preferred
Computer and database skills are preferred
About Vanderbilt University
Vanderbilt University, located in Nashville, Tennessee, is a top-15 private research university offering a full range of undergraduate, graduate and professional degrees. Vanderbilt is situated on a 330-acre campus near the thriving city center, serving more than 12,000 students and employing almost 7,000 faculty and staff. The university's students, staff, and faculty frequently cite Nashville and the surrounding area as one of the many perks of being a part of the Vanderbilt community. Vanderbilt University is a place where your expertise will be valued, your knowledge expanded, and your abilities challenged. It is a place where your diversity is sought and celebrated. Vanderbilt was recently named as one of "America's Best Large Employers" and the top employer in Tennessee and the Nashville metropolitan area in 2019 (Forbes).
About Vanderbilt Benefits
Vanderbilt University offers a competitive, flexible benefits package including health, dental, vision, life, accidental death & dismemberment, disability insurance, paid time off, and a 403(b) retirement plan with employer match. Vanderbilt offers tuition assistance to employees, spouses, and dependent children.
Commitment to Equity, Diversity and Inclusion
Vanderbilt University is committed to achieving the goal of a diverse and inclusive academic community of faculty, staff, and students. We seek individuals who are committed to this goal and our campus values.
Internal Number: 1901830
About Vanderbilt University
Vanderbilt University is a center for scholarly research, informed and creative teaching, and service to the community and society at large. Vanderbilt will uphold the highest standards and be a leader in the quest for new knowledge through scholarship, the dissemination of knowledge through teaching and outreach, and the creative experimentation of ideas and concepts. In pursuit of these goals, Vanderbilt values most highly intellectual freedom that supports open inquiry, equality, compassion, and excellence in all endeavors.